Our Team
Directors
Heidi Rehm, PhDHeidi is the co-director for the Broad Center for Mendelian Genomics. She is also the chief genomics officer of the Department of Medicine at Massachusetts General Hospital and a professor at Harvard Medical School. She built the Laboratory for Molecular Medicine at Partners HealthCare Personalized Medicine and directed it until 2018. She is a strong advocate and pioneer of open science and data sharing through leadership roles in the Clinical Genome (ClinGen) Resource and the Global Alliance for Genomics and Health.
Anne O’Donnell-Luria, MD PhDAnne is co-director for the Broad Center for Mendelian Genomics. She obtained her MD/PhD from Columbia University and is a board-certified clinical genetics and metabolism physician and pediatrician who sees patients at Boston Children's Hospital. Her current research focuses on the use of exome and genome sequence data to identify genetic variation in health and disease to improve rare disease diagnosis and better understand incomplete penetrance.
Michael E. Talkowski, PhD
Mike is the co-director for the Broad Center for Mendelian Genomics. He is also the Director of the Center for Genomic Medicine at Massachusetts General Hospital, Professor of Neurology at Harvard Medical School, and a Broad Institute Member. Mike leads a molecular and computational genomics research program that is focused on the discovery and characterization of genetic variation in human disease. He has made seminal contributions to understanding the relationship between the structure and function of the human genome and its relationship to neurodevelopmental and neuropsychiatric disorders and rare Mendelian disorders.
Kaitlin Samocha, PhD
Kaitlin received her Ph.D. in Genetics and Genomics in 2016 from Harvard University under the supervision of Dr. Mark Daly. She trained as a postdoctoral fellow with Dr. Matthew Hurles at the Wellcome Sanger Institute and was a College Research Associate at St. John’s College, Cambridge. Kaitlin is an Assistant Professor in the Center for Genomic Medicine at Massachusetts General Hospital and an Associated Scientist at the Broad Institute. The focus of her research career has been on developing methods and statistical tools to improve the interpretation of genetic variation, particularly rare variation. This work has included a sequence-context based mutational model, frameworks to evaluate de novo (newly arising) variation, and metrics to quantify selective constraints against damaging variation.
Monica Wojcik, MDMonica is an attending neonatologist and geneticist at Boston Children's Hospital and an associate member of the Broad Institute. Her research focuses on equitable and effective implementation of genomic medicine, particularly for critically ill neonates as well as infants and children with rare diseases. She is the Neonatal Genomics Program director and co-director of the Fetal Precision Genetics program at Boston Children's Hospital. Monica received her AB in Chemistry from Princeton University in 2007 and her MD from Harvard Medical School. She subsequently completed pediatric residency training at the Boston Combined Residency Program and combined fellowship training in neonatal-perinatal medicine and medical genetics at Boston Children's Hospital/Harvard Medical School. She completed her MPH degree at the Harvard TH Chan School of Public Health with a focus on clinical effectiveness and health services research.
Our Team
Please visit the Translational Genomics Group and Talkowski Lab for our current list of staff.